Need structural data, sequence info, or pharmacology on peptides? These databases actually have it. We checked which ones are live, maintained, and useful for peptide researchers.
How we evaluated: This page records the public sources reviewed for each entry and states the limits of those records.
Comprehensive protein sequence and annotation data. Has a dedicated peptide search.
What we verified
Confirmed live, Release 2026_02. Has a dedicated 'Peptide search' feature for sequence-based queries.
COA claims
Protein sequence database with functional annotation, structural cross-references, and peptide-specific search tools.
Community notes
Used by researchers for sequence verification and protein context. Less commonly referenced in casual community discussions: more of a serious research tool.
The good
Dedicated peptide search feature
Comprehensive protein annotation
Actively maintained
Free for academic use
The bad
Protein-focused, not peptide-focused
Complex interface
Overkill for most community use cases
Verdict
If you need to verify a peptide's protein context or find the parent protein, UniProt is the answer. Not for casual lookups.
FDA-approved therapeutic peptide database with pharmacology data. Another hidden gem.
What we verified
Confirmed live. Contains FDA-approved therapeutic peptides with pharmacology data including half-life and PK data.
COA claims
Therapeutic peptide database with pharmacology data (half-life, PK, administration route), FDA approval status, and clinical data.
Community notes
Virtually unknown in biohacker communities. Valuable for finding pharmacokinetic data on approved peptide drugs like semaglutide and tirzepatide.
The good
FDA-approved peptides
Pharmacokinetic data (half-life, PK)
Administration route data
Free
The bad
Limited to FDA-approved peptides
Doesn't cover research peptides
Academic interface
Verdict
If you need real PK data on approved peptides (semaglutide, tirzepatide), this is where to find it. Useless for research peptides that aren't FDA-approved.
Best for bioactivity data. Actively maintained: updated same day we checked.
What we verified
Confirmed actively maintained: blog post dated July 9, 2026 (same day as visit). Bioactivity-focused database.
COA claims
Bioactivity database with drug-target interactions, IC50 values, and assay data. Covers peptides and small molecules.
Community notes
Known in pharmacology research circles. Useful for finding actual bioactivity data: not just structure, but what the compound does to targets.
The good
Bioactivity data (IC50, Ki values)
Actively maintained
Free
Covers peptides and small molecules
Drug-target interactions
The bad
Complex interface
Not peptide-specific
Academic-focused
Verdict
If you need actual bioactivity numbers: not just 'this compound does X' but at what concentration: ChEMBL is the database. Actively maintained, which matters.