Peer reviewed

mTOR inhibition improves immune function in the elderly

Double-blind, placebo-controlled trial (Mannick et al.) showing that low-dose rapamycin analog (everolimus) improved immune response to influenza vaccine in older adults, providing early human translational evidence.

Science Translational MedicinePublished 2014-12-24Accessed 2026-07-01

Open original source

Registry record

Source metadata

Publisher
Science Translational Medicine
Source type
Peer reviewed
Registry ID
nature-mannick-2014-rapamycin-immune

Interpretation boundary

What this record can and cannot establish

Inclusion in the registry is not endorsement. The record supports only the claims that fit its design, population, date, and scope. Company, media, and community records can document that a claim was made without proving the claim itself.