Peer reviewed
mTOR inhibition improves immune function in the elderly
Double-blind, placebo-controlled trial (Mannick et al.) showing that low-dose rapamycin analog (everolimus) improved immune response to influenza vaccine in older adults, providing early human translational evidence.
Science Translational MedicinePublished 2014-12-24Accessed 2026-07-01
Registry record
Source metadata
- Publisher
- Science Translational Medicine
- Source type
- Peer reviewed
- Registry ID
nature-mannick-2014-rapamycin-immune
Interpretation boundary
What this record can and cannot establish
Inclusion in the registry is not endorsement. The record supports only the claims that fit its design, population, date, and scope. Company, media, and community records can document that a claim was made without proving the claim itself.