Peer reviewed

mTOR inhibition improves immune function in the elderly

Double-blind, placebo-controlled trial (Mannick et al.) showing that low-dose rapamycin analog (everolimus) improved immune response to influenza vaccine in older adults, providing early human translational evidence.

Science Translational MedicinePublished Dec 24, 2014Accessed Jul 1, 2026

Open original source

Registry record

Source metadata

Publisher: Science Translational Medicine
Source type: Peer reviewed
Registry ID: nature-mannick-2014-rapamycin-immune

Source usage

Linked from 2 pages

Evidence curation

Best Compounds for Longevity Research

Guide

Peptide Category Explainers: How Every Compound Class on This Site Is Defined

Interpretation boundary

What this record can and cannot establish

Inclusion in the registry is not endorsement. The record supports only the claims that fit its design, population, date, and scope. Company, media, and community records can document that a claim was made without proving the claim itself.