Peer reviewed

Tirzepatide and Semaglutide for Obesity in Adults (SURMOUNT-5)

Head-to-head Phase 3 trial (Garvey et al., 2024) directly comparing tirzepatide and semaglutide for weight loss in adults with obesity. Reported greater mean weight loss with tirzepatide (approximately 20.9%) than semaglutide (approximately 17.3%) at 72 weeks.

New England Journal of MedicinePublished 2024-12-04Accessed 2026-07-08

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Publisher
New England Journal of Medicine
Source type
Peer reviewed
Registry ID
nejm-tirzepatide-surmount5-2024

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